Process R&D

Our process development services are focused on the need to develop scalable and robust synthetic routes under a tight timeline. We scale up our clients' chemistry and/or suggest, develop and optimize alternate synthetic routes. PharmaZell will provide you with the appropriate solution to meet your expectations on quality, quantity and regulatory needs within the relevant timeline requirements.

Our process development services include:

  • Chemical route selection
  • Process optimization and scale-up
  • HSE assessment
  • Process validation
  • Development of analytical methods and validation
  • Regulatory filings

Our services include all areas of Advanced Intermediates and API product development and cGMP compliant manufacturing – from few grams to multi-ton scale.

In addition, we offer API particle control (i.e. polymorphism, tailor-made particle size distributions and crystal shape) via optimization of crystallization processing, drying and/or milling and micronization.

PharmaZell provides a wide range of diverse technologies, such as batch and continuous processes (including micro reactor technology) numerous chemical reactions like nitrations, halogenations, hydrogenations, electrochemical reactions, electrodialysis and reactions with organo-metallic compounds, etc.

Furthermore we offer solutions for stereoselective synthesis problems by applying biocatalytic/enzymatic reaction expertise.